N-ALPHA-TERT-BUTYLOXYCARBONYL-L-GLUTAMIC ACID DI-METHYL DIESTER - Names and Identifiers
N-ALPHA-TERT-BUTYLOXYCARBONYL-L-GLUTAMIC ACID DI-METHYL DIESTER - Physico-chemical Properties
Molecular Formula | C12H21NO6
|
Molar Mass | 275.3 |
Density | 1.117±0.06 g/cm3(Predicted) |
Melting Point | 43.0 to 47.0 °C |
Boling Point | 370.9±32.0 °C(Predicted) |
Flash Point | 178.1°C |
Solubility | Chloroform (Slightly), DMSO (Slightly) |
Vapor Presure | 1.07E-05mmHg at 25°C |
Appearance | Liquid |
Color | Colorless to pale yellow |
pKa | 10.86±0.46(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.452 |
N-ALPHA-TERT-BUTYLOXYCARBONYL-L-GLUTAMIC ACID DI-METHYL DIESTER - Introduction
(R)-N-Boc-glutamic acid-1,5-dimethyl ester is an organic compound with a molecular formula of C12H20N2O6 and a molecular weight of 296.3g/mol. The following is an introduction to the nature, use, formulation and safety information of (R)-N-Boc-glutamic acid-1,5-dimer ester:
Nature:
-Appearance:(R)-N-Boc-glutamic acid-1,5-dimethyl ester is a white solid.
-Solubility: It has good solubility and high solubility in some organic solvents (such as dimethylformamide, dichloromethane, etc.).
-melting point:(R)-the melting point of N-Boc-glutamic acid-1,5-dimer ester is about 70-75°C.
Use:
- (R)-N-Boc-glutamic acid-1, 5-dimethylester is a commonly used amino acid compound. It is usually used as an intermediate in organic synthesis, and is widely used in drug synthesis and bioactive substances research.
Preparation Method:
- (R)-N-Boc-glutamic acid-1,5-dimethyl ester can be obtained by chemical modification of L-glutamic acid. A common preparation method is to first react L-glutamic acid with tert-butyl titanium dioxide (Boc2O) to give N-tert-butoxycarbonyl-L-glutamic acid, which is then reacted with methyl formate to give (R)-N-Boc-glutamic acid-1,5-dimethyl ester.
Safety Information:
- (R)-N-Boc-glutamic acid-1, 5-dimer ester is generally relatively safe under normal operating conditions. But as a chemical, still need to pay attention to the following matters:
-Avoid contact with skin and eyes to prevent inhalation and ingestion.
-Wear appropriate chemical protective gloves, goggles and protective clothing during use.
-Operate in a well-ventilated place to avoid dust and smoke.
-Storage should be sealed and kept away from fire and oxidizing agents.
-If you accidentally splash into your eyes or skin, rinse immediately with plenty of water and seek medical help.
-If taken by mistake or inhaled too much, seek medical attention immediately.
Last Update:2024-04-09 19:05:50